How can I boot a existing VHD?

[Albert Voss]

I have several external USB devices (cheap SSDs in UGREEN USB 3.0 enclosures) that can boot to Windows 10. But as most of our PCs are on 1809 already I cannot simply clone those PCs to an WinToUSB device. HASLEO says that to produce a bootable USB device one can use VHDs. I tried with differrent PC backups that I made with Disk2VHD and so far use with VMware Player installed on the device specific external SSD. I hope that I could increase speed when booting these VHDs directly and not via a virtual machine player.
Is this possible with WinToUSB?